PrEP Impact Trial

Update – April 2020: We understand the decision has been made to make PrEP routinely available across England. As a service, we are currently responding to Covid-19 (Coronavirus) and will therefore provide further details about access to PrEP at a later date.

Spaces on the PrEP Impact Trial for gay and bisexual men are now FULL at all of the sites within Solent Sexual Health. Spaces remain in all sites for heterosexuals. Please see information below about how to access PrEP if you have not been able to get a place on the Impact Trial.

The NHS in England is not able to supply PrEP to anyone outside of clinical trials. As a service, Solent NHS Trust Sexual Health are allocated a set number of places on the trial. Due to the restriction of numbers and overwhelming demand, places cannot be guaranteed onto this trial, even if you meet the eligibility criteria. We understand that anyone wishing to access PrEP is making an important decision in looking after their own health and wellbeing. Therefore as a service we are here to support you if you have any questions about using PrEP or accessing PrEP outside of trials. If you do access PrEP from other sources, we are able to provide you with safety monitoring and give you advise on usage. We will also provide routine STI testing and other Sexual Health services as part of your journey with PrEP.


How can I obtain PrEP if I am not able to obtain it via this trial?

Unfortunately the NHS is not able to supply PrEP to anyone outside of clinical trials.

For information about other ways of acquiring PrEP we suggest you visit the iwantprepnow website

If you do acquire PrEP from another source, please make an appointment and discuss your PrEP use with the sexual health team.  We will be able to advise you on its use, and provide the safety monitoring required.

Terrence Higgins Trust (THT) has set up a fund to give financial assistance to people who are not able to access PrEP on the NHS and who cannot afford to buy it themselves online. The THT Mags Portman PrEP Access Fund will provide PrEP for up to 1,000 people and will be open until the end of the Impact Trial or until PrEP is commissioned on the NHS, whichever comes first.

 Applicants for the Mags Portman PrEP Access Fund need to be:

  • aged over 16 years
  • resident in England or Northern Ireland
  • clinically eligible for PrEP (see Impact trial eligibility below)
  • able to confirm HIV negative status and engagement with sexual health services
  • able to demonstrate the need for support by submitting documents showing that they have no income or are in receipt of benefits.

 More information on the fund and how to apply can be found here.


What is the PrEP Impact Trial?

PrEP (pre-exposure prophylaxis against HIV) is a medication that can be used by people who are HIV negative, but at high risk of HIV, to dramatically reduce their chance of catching HIV.  It has been shown to be highly effective in previous trials.   The PrEP Impact Trial will recruit 10,000 people at high risk of HIV acquisition across England, and offer them PrEP. 

Since December 2017 Solent NHS Trust Sexual Health services have enrolled more than 140 people onto the trial.

As this is a trial and not routine NHS service, we were only allocated a limited number of places by the PrEP Impact Trial team. Places have been allocated separately for men who have sex with men (MSM) and other people who might benefit from PrEP.

The findings from this study will help NHS England and Local Authorities make decisions about how PrEP could be provided in the future. It is anticipated that a national programme will be put in place and that PrEP will be available to all who are eligible.

Please visit the PrEP Impact Trial website for further information on eligibility.


Who will be eligible for the trial?

Only those who are at very high risk of catching HIV are eligible to join.

People aged 16 or over who meet one of the following criteria:

A. Men and transgender women who:

  • Have sex with men
  • AND have had an HIV negative test during in the preceding year
  • AND report condomless sex (excluding oral) in the previous 3 months
  • AND are likely to continue having condomless sex (excluding oral) in the next 3 months

 B. HIV negative partners of an HIV positive person when:

  • The HIV positive partner is not known to be virally suppressed (<200 copies/ml for 6 months or more)
  • AND condomless sex (excluding oral) is anticipated before treatment of the HIV positive partner takes effect

C. Other HIV negative people assessed to be at high risk of HIV acquisition.

  • This may include people having condomless sex (excluding oral) with multiple partners from parts of the world where HIV is common (such as Southern Africa, Southeast Asia and the Caribbean), and commercial sex workers or their clients who report regular condomless sex.


How do I get involved in the trial?

If you believe you are eligible for this trial, please read through the participant information sheet available on the PrEP impact trial website here

We also suggest you read the guide to PrEP available here.

Please note that Solent Sexual Health only has a limited number of spaces to allocate to this trial.  Meeting the eligibility criteria does not guarantee you a place on this trial.


  • If you have had a negative HIV test in the last year – please phone 0300 300 2016 and state that you are interested in the PrEP trial.  A member of the trial team will contact you to confirm your eligibility for the trial, and arrange an appointment with one of the trial clinicians. Currently there is a considerable waiting list, so it may be a few weeks before you are contacted by the trial team.
  • If your latest HIV test is more than a year ago – Please book an appointment for an HIV test (and other STI tests if indicated).  At your appointment please discuss the PrEP trial, and if you are eligible the clinician will arrange for a member of the trial team to contact you once your HIV result is known.