PrEP Impact Trial
Update – April 2019. Solent Sexual Health has new places available on the trial for gay and bisexual men in all 3 trial sites (Basingstoke, Southampton, Portsmouth). Spaces remain in all sites for heterosexuals. Please see the information below for eligibility criteria and how to express your interest in a trial place.
What is the PrEP Impact Trial?
PrEP (pre-exposure prophylaxis against HIV) is a medication that can be used by people who are HIV negative, but at high risk of HIV, to dramatically reduce their chance of catching HIV. It has been shown to be highly effective in previous trials. The PrEP Impact Trial will recruit 10,000 people at high risk of HIV acquisition across England, and offer them PrEP.
Who will be eligible for the trial?
People aged 16 or over who meet one of the following criteria:
A. Men and transgender women who:
- Have sex with men
- AND have had an HIV negative test during in the preceding year
- AND report condomless sex (excluding oral) in the previous 3 months
- AND are likely to continue having condomless sex (excluding oral) in the next 3 months
B. HIV negative partners of an HIV positive person when:
- The HIV positive partner is not known to be virally suppressed (<200 copies/ml for 6 months or more)
- AND condomless sex (excluding oral) is anticipated before treatment of the HIV positive partner takes effect
C. Other HIV negative people assessed to be at high risk of HIV acquisition. This may include people having condomless sex (excluding oral) with multiple partners from parts of the world where HIV is common (such as Southern Africa, Southeast Asia and the Caribbean), and commercial sex workers or their clients who report regular condomless sex.
How do I get involved in the trial?
If you believe you are eligible for this trial, please read through the participant information sheet available on the PrEP impact trial website here.
We also suggest you read the guide to PrEP available here.
Please note that Solent Sexual Health only has a limited number of spaces to allocate to this trial. Meeting the eligibility criteria does not guarantee you a place on this trial.
- If you have had a negative HIV test in the last year – please phone 0300 300 2016 and state that you are interested in the PrEP trial. A member of the trial team will contact you to confirm your eligibility for the trial, and arrange an appointment with one of the trial clinicians. Currently there is a considerable waiting list, so it may be a few weeks before you are contacted by the trial team.
- If your latest HIV test is more than a year ago – Please book an appointment for an HIV test (and other STI tests if indicated). At your appointment please discuss the PrEP trial, and if you are eligible the clinician will arrange for a member of the trial team to contact you once your HIV result is known.
How can I obtain PrEP if I am not able to obtain it via this trial?
Unfortunately the NHS is not able to supply PrEP to anyone outside of clinical trials.
For information about other ways of acquiring PrEP we suggest you visit the iwantprepnow website.
If you do acquire PrEP from another source, please make an appointment and discuss your PrEP use with the sexual health team. We will be able to advise you on its use, and provide the safety monitoring required.
Terrence Higgins Trust (THT) has set up a fund to give financial assistance to people who are not able to access PrEP on the NHS and who cannot afford to buy it themselves online. The THT Mags Portman PrEP Access Fund will provide PrEP for up to 1,000 people and will be open until the end of the Impact Trial or until PrEP is commissioned on the NHS, whichever comes first.
Applicants need to be:
- aged over 16 years
- resident in England or Northern Ireland
- clinically eligible for PrEP (see Impact trial eligibility below)
- able to confirm HIV negative status and engagement with sexual health services
- able to demonstrate the need for support by submitting documents showing that they have no income or are in receipt of benefits.
More information on the fund and how to apply can be found here.